Talk:Y RNA

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section on species distribution[edit]

We could make a seperate section on species distribution. I did this for the hammerhead ribozyme entry. Does it also make sense to have a section on structure, and another on function? Anyway I really like what's done so far. Alexbateman 16:38, 17 May 2007 (UTC)[reply]

Hi Alex! I'm so glad that you like it. :) I wouldn't worry about italicizing the species names right now — I think we can do that automatically. However, it would be helpful to know of any other sections (such as "species distribution" or "structure") that you'd like to have included in the pages, so that you all wouldn't have to input them by hand. Talk to you soon, Willow 18:16, 17 May 2007 (UTC)[reply]

Hi Willow, In putting the section titles isn't such a chore, I find thinking of what to put in them the hard bit :) Won't the stubs look a bit odd with empty sections in? By the way, the stubs you've created so far look mighty fine! Thanks for your help with this. I'm now very excited about this project and hope we can keep this momentum going once we start to get community input. Alexbateman 08:13, 18 May 2007 (UTC)[reply]

Ro vs Calreticulin[edit]

Hi Narayanese. I can't find any evidence for a relationship between Ro and Calreticulin. I've removed the links you added. Unless you can find a reference showing t his link? Below are the text from Pfam descriptions:

'Calreticulin' is a high-capacity calcium-binding protein which is present in most tissues and located at the periphery of the endoplasmic (ER) and the sarcoplamic reticulum (SR) membranes. It probably plays a role in the storage of calcium in the lumen of the ER and SR and it may well have other important"

'Ro ribonucleoprotein' contains the follwing Pfam domain family: 'TROVE' (PF05731), represented by protein RO60_HUMAN (P10155) 538 AA. This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-binding.--Ppgardne 15:09, 2 January 2008 (UTC)

I though since Calreticulin also involved in systemic lupus erythematosus and I saw Calreticulin being called Ro antigen they were the same... I guess I drew a conclusion too fast. Narayanese (talk) 16:14, 17 March 2008 (UTC)[reply]