Talk:Vilazodone

This is the talk page for discussing improvements to the Vilazodone article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Pharmacology Low‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Low	This article has been rated as Low-importance on the project's importance scale.

Chemicals Low‑importance

	This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles
Low	This article has been rated as Low-importance on the project's importance scale.

Medicine Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Low	This article has been rated as Low-importance on the project's importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Vilazodone.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

SSRI?[edit]

http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=4c55ccfb-c4cf-11df-851a-0800200c9a66#section-11

"VIIBRYD Tablets for oral administration contain polymorph Form IV vilazodone hydrochloride (HCl), a selective serotonin reuptake inhibitor and a 5HT1A receptor partial agonist."

Is it really an SSRI? If yes, please add to article.--4h8s (talk) 14:58, 3 October 2013 (UTC)[reply]

It’s another class technically. Think of it as ssri 2.0. Most the new drugs hit SERT then also try and hit 5-HT1A and maybe a few others to get a favorable effect profile. Technically a SERM serotonin receptor modulator. Eg it has multiple effects in the serotonin system - and likely other monoamine systems. Dopamine norepinephrine epinephrine (adrenergic alpha, beta) etc Gizmo.AT (talk) 04:08, 31 August 2020 (UTC)[reply]

To clarify - anything that has a low number next to “SERT” in the pharmacokinetics section is technically an SSRI in the “lay” parlance. E.g it has a significant effect at the reuptake transporter Gizmo.AT (talk) 04:11, 31 August 2020 (UTC)[reply]

Clinically insignificant effects at the NET receptor[edit]

Yea freaking right. Skim the side effects and effects, and the NET activity (or downstream effects) are rather important here. Speaking from experience here. Was a bit surprised at how activating and sympathomimetic this was. Not in a good way. D/c’d after a month or two of sweaty diarrhea. Gizmo.AT (talk) 04:04, 31 August 2020 (UTC)[reply]