Talk:Immunoglobulin A

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Most abundant immunoglobulin[edit]

The article states More IgA is produced in mucosal linings than all other types of antibody combined (...). However the article on IgG states IgG is the most abundant immunoglobulin. Which one is correct? Is the article on IgA only referring to mucosal linings? How much IgG is there compared to IgA (overall/blood/gut)?

I have little to no experience in immunology, maybe someone could clarify this.

Cheers, JS 129.67.77.81 (talk) 17:15, 16 November 2010 (UTC)[reply]

Added This accumulates ... 75% of total ... (according to Macpherson and Slack, 2007).

Cheers, JS 129.67.77.81 (talk) 15:16, 24 November 2010 (UTC)[reply]

I found this web site which cites a normal range for IgA and IgG, etc: http://www.lymphomation.org/tests-immunoglobulins.htm

Cheers RedEagle07RedEagle07 (talk) 16:18, 12 January 2011 (UTC)[reply]

IgG is measured in serum at the 6 to 14 g/L range. IgA is measured in serum in the 1.5 to 3 g/L range (approx).This is only a concentration, however, not a rate of synthesis, which may be quite different. Most IgA produced will be lost to the bodies exterior, including the intestinal lumen.So it will be influenced/stimulated essentially by external conditions. — Preceding unsigned comment added by 84.246.202.164 (talk) 20:33, 30 September 2011 (UTC)[reply]

Use as diagnostic[edit]

How about its role in an diseases diagnosis? — Preceding unsigned comment added by 109.206.137.161 (talk) 11:48, 11 August 2016 (UTC)[reply]

"crucial"[edit]

The introduction states that IgA is crucial but in humans selective IgA deficiency is usually asymptomatic suggesting it plays a fairly minor role in most individuals. Curious what others think. Adhiyana (talk) 16:29, 11 February 2022 (UTC)[reply]