Talk:7-Methyl-α-ethyltryptamine

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Important member of series missing?[edit]

I talked with Dr. Lednicer (ex-head of CNS group at Upjohn) and after AMT & AET, 7,α-DMT was produced before 7-methyl-α-ethyl tryptamine (as patent shows). Shouldn't it be added? I think it's also important to note that this class is chiral. The (S) isomers are DRI/SRIs with 5HT2a affinity making them hallucinogens. The (R) isomers are also DRI/SRIs but they don't have 5HT2a affinity so that the subjective effects make them entactogens. The fact that so little research has gone into the activity of the 2 enantiomers. From the limited amount of data we had to share, it appears that the (S) isomers are responsible for MAOI activity. There are a series of Upjohn from 1959 to 1965 that covers them all. Would a QSAR diagram be of benefit? — Preceding unsigned comment added by 81.99.74.135 (talk) 10:54, 1 February 2019 (UTC)[reply]