TCP11

TCP11
Identifiers
Aliases	TCP11, D6S230E, FPPR, t-complex 11
External IDs	OMIM: 186982 MGI: 98544 HomoloGene: 8433 GeneCards: TCP11
Gene location (Human)
Chr.	Chromosome 6 (human)
End	35,148,610 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	28,080,639 bp
RNA expression pattern
	Top expressed in
	sperm; ; oocyte; ; secondary oocyte; ; right uterine tube; ; amniotic fluid; ; bronchial epithelial cell; ; right coronary artery; ; ovary; ; prefrontal cortex; ; ganglionic eminence;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; lens; ; motor neuron; ; molar; ; right lung lobe; ; islet of Langerhans; ; atrioventricular valve; ; cumulus cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; membrane; acrosomal vesicle; cytoplasmic vesicle; sperm flagellum; cell projection; sperm midpiece; motile cilium; cilium;
Biological process	cell differentiation; spermatogenesis; multicellular organism development; protein kinase A signaling; regulation of cAMP-mediated signaling; regulation of sperm capacitation;
	Sources:Amigo / QuickGO
Orthologs
	6954
	21463
	ENSG00000124678
	ENSMUSG00000062859
	Q8WWU5
	Q01755
NM_001093728; NM_001261817; NM_001261818; NM_001261819; NM_001261820;
	NM_001261821; NM_018679
	NM_001085555; NM_013687; NM_001357681; NM_001374620; NM_001374621
NP_001248746; NP_001248747; NP_001248748; NP_001248749; NP_001248750;
	NP_061149; NP_001353252; NP_001353253; NP_001353254; NP_001353255; NP_001353256; NP_001353257; NP_001353258; NP_001353259; NP_001353260; NP_001353261; NP_001357616
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

T-complex protein 11 homolog is a protein that in humans is encoded by the TCP11 gene.^[5]^[6]^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124678 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062859 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Nov 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID 1427894.
^ Ma Y, Zhang S, Xia Q, Zhang G, Huang X, Huang M, Xiao C, Pan A, Sun Y, Lebo R, Milunsky A (Jan 2002). "Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide". Molecular Human Reproduction. 8 (1): 24–31. doi:10.1093/molehr/8.1.24. PMID 11756566.
^ "Entrez Gene: TCP11 t-complex 11 (mouse)".

Further reading[edit]

Ma YX, Zhang SZ, Wu QQ, Sun Y, Qiu WM, Xu WM (Apr 2003). "[Cloning, expression, and alternative splicing of the novel isoform of hTCP11 gene]". Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 25 (2): 122–8. PMID 12905703.
Ma YX, Zhang SZ, Wu QQ, Sun Y (Feb 2003). "[Cloning, expression and alternative splicing of a novel isoform of human TCP11b gene]". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao Acta Biochimica et Biophysica Sinica. 35 (2): 182–8. PMID 12545228.
Fraser LR, Hosseini R, Hanyalogou A, Talmor A, Dudley RK (Nov 1997). "TCP-11, the product of a mouse t-complex gene, plays a role in stimulation of capacitation and inhibition of the spontaneous acrosome reaction". Molecular Reproduction and Development. 48 (3): 375–82. doi:10.1002/(SICI)1098-2795(199711)48:3<375::AID-MRD11>3.0.CO;2-V. PMID 9322250. S2CID 42009443.
Mazarakis ND, Nelki D, Lyon MF, Ruddy S, Evans EP, Freemont P, Dudley K (Feb 1991). "Isolation and characterisation of a testis-expressed developmentally regulated gene from the distal inversion of the mouse t-complex". Development. 111 (2): 561–71. doi:10.1242/dev.111.2.561. PMID 1893875.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124678 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000062859 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1427894-5] Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Nov 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID 1427894.

[pmid11756566-6] Ma Y, Zhang S, Xia Q, Zhang G, Huang X, Huang M, Xiao C, Pan A, Sun Y, Lebo R, Milunsky A (Jan 2002). "Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide". Molecular Human Reproduction. 8 (1): 24–31. doi:10.1093/molehr/8.1.24. PMID 11756566.

[entrez-7] "Entrez Gene: TCP11 t-complex 11 (mouse)".

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