Shc binding and spindle associated 1 like

SHCBP1L
Identifiers
Aliases	SHCBP1L, C1orf14, GE36, SHC binding and spindle associated 1 like
External IDs	MGI: 1919086 HomoloGene: 12800 GeneCards: SHCBP1L
Gene location (Human) Chr. Chromosome 1 (human) Band 1q25.3 Start 182,899,865 bp End 182,953,525 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 G3 Start 153,300,908 bp End 153,328,320 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm gastric mucosa embryo ganglionic eminence human musculoskeletal system muscular system muscle muscle right coronary artery adipose tissue Top expressed in spermatocyte spermatid seminiferous tubule otolith organ utricle secondary oocyte substantia nigra ovary olfactory tubercle ventromedial nucleus More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 81626 71836 Ensembl ENSG00000157060 ENSMUSG00000042708 UniProt Q9BZQ2 Q3TTP0 RefSeq (mRNA) NM_030933 NM_001345928 NM_001033162 RefSeq (protein) NP_001332857 NP_112195 NP_001028334 Location (UCSC) Chr 1: 182.9 – 182.95 Mb Chr 1: 153.3 – 153.33 Mb PubMed search
Wikidata
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SHC binding and spindle associated 1 like is a protein that in humans is encoded by the SHCBP1L gene.

Function

This gene encodes a Src homology 2 domain-binding protein 1-like protein. The encoded protein interacts with heat shock 70 kDa protein 2 and may be involved in maintaining spindle integrity during meiosis. This gene is located in region of chromoso0me 1 encompassing a prostate cancer susceptibility locus. [provided by RefSeq, Sep 2016].

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.