ODE-CDV

From Wikipedia, the free encyclopedia
ODE-CDV
Names
Preferred IUPAC name
2-(Octadecyloxy)ethyl ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C28H54N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-36-21-22-38-39(34,35)25-37-26(24-32)23-31-19-18-27(29)30-28(31)33/h18-19,26,32H,2-17,20-25H2,1H3,(H,34,35)(H2,29,30,33)/t26-/m0/s1
    Key: BLYNHZVAZVOTGV-SANMLTNESA-N
  • InChI=1/C28H54N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-36-21-22-38-39(34,35)25-37-26(24-32)23-31-19-18-27(29)30-28(31)33/h18-19,26,32H,2-17,20-25H2,1H3,(H,34,35)(H2,29,30,33)/t26-/m0/s1
    Key: BLYNHZVAZVOTGV-SANMLTNEBA
  • CCCCCCCCCCCCCCCCCCOCCOP(=O)(CO[C@@H](Cn1ccc(nc1=O)N)CO)O
Properties
C28H54N3O7P
Molar mass 575.728 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

ODE-CDV (octadecyloxyethyl-cidofovir) is a cidofovir derivative with antiviral activity.[1]

References[edit]

  1. ^ Kern, E. R.; Hartline, C.; Harden, E.; Keith, K.; Rodriguez, N.; Beadle, J. R.; Hostetler, K. Y. (2002). "Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir". Antimicrobial Agents and Chemotherapy. 46 (4): 991–995. doi:10.1128/AAC.46.4.991-995.2002. PMC 127114. PMID 11897580.