MIR4640

MIR4640
Identifiers
Aliases	MIR4640, microRNA 4640
External IDs	GeneCards: MIR4640
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.33 Start 30,890,883 bp End 30,890,972 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle putamen Brodmann area 9 left coronary artery left ventricle smooth muscle tissue body of stomach kidney hippocampus proper ascending aorta n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 100616237 n/a Ensembl ENSG00000284370 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 6: 30.89 – 30.89 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

MicroRNA 4640 is a non-coding RNA in humans that is encoded by the MIR4640 gene.

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].