List of signaling peptide/protein receptor modulators
This is a list of signaling peptide/protein receptor modulators
Adiponectin[edit]
AdipoR1[edit]
- Agonists: Peptide: Adiponectin
- ADP-355
- ADP-399; Non-peptide: AdipoRon
- (–)-Arctigenin
- Arctiin
- Gramine
- Matairesinol
- Antagonists: Peptide: ADP-400
AdipoR2[edit]
- Agonists: Peptide: Adiponectin
- ADP-355
- ADP-399; Non-peptide: AdipoRon
- Deoxyschizandrin
- Parthenolide
- Syringing
- Taxifoliol
- Antagonists: Peptide: ADP-400
Angiotensin[edit]
- See here instead.
Bradykinin[edit]
- Agonists: Bradykinin
- Kallidin
[edit]
- Agonists: Amylin
- CGRP
- Pramlintide
- Antagonists: Atogepant
- BI 44370 TA
- CGRP (8-37)
- MK-3207
- Olcegepant
- Rimegepant
- SB-268262
- Telcagepant
- Ubrogepant
- Antibodies: Eptinezumab
- Erenumab
- Fremanezumab
- Galcanezumab
Cholecystokinin[edit]
CCKA[edit]
- Agonists: Cholecystokinin
- Antagonists: Amiglumide
- Asperlicin
- Devazepide
- Dexloxiglumide
- Lintitript
- Lorglumide
- Loxiglumide
- Pranazepide
- Proglumide
- Tarazepide
- Tomoglumide
CCKB[edit]
- Agonists: Cholecystokinin
- CCK-4
- Gastrin
- Pentagastrin (CCK-5)
- Antagonists: Ceclazepide
- CI-988 (PD-134308)
- Itriglumide
- L-365,360
- Netazepide
- Proglumide
- Spiroglumide
Unsorted[edit]
- Antagonists: Nastorazepide
Corticotropin-releasing hormone receptor[edit]
CRF1[edit]
- Antagonists: Antalarmin
- Astressin-B
- CP-154,526
- Emicerfont
- Hypericin
- LWH-234
- NBI-27914
- NBI-74788
- Pexacerfont
- R-121919
- TS-041
- Verucerfont
CRF2[edit]
- Antagonists: Astressin-B
Cytokine[edit]
See here instead.
Endothelin[edit]
- Agonists: Endothelin 1
- Endothelin 2
- Endothelin 3
- IRL-1620
- Sarafotoxin
- Antagonists: A-192621
- Ambrisentan
- Aprocitentan
- Atrasentan
- Avosentan
- Bosentan
- BQ-123
- BQ-788
- Clazosentan
- Darusentan
- Edonentan
- Enrasentan
- Fandosentan
- Feloprentan
- Macitentan
- Nebentan
- Sitaxentan
- Sparsentan
- Tezosentan
- Zibotentan
Galanin[edit]
GAL1[edit]
- Antagonists: C7
- Dithiepine-1,1,4,4-tetroxide
- Galantide (M15)
- M32
- M35
- M40
- SCH-202596
GAL2[edit]
GAL3[edit]
- Agonists: Galanin
- Galanin (1-15)
- Galmic
- Galnon
- Antagonists: C7
- Galantide (M15)
- GalR3ant
- HT-2157
- M32
- M35
- M40
- SNAP-37889
- SNAP-398299
Ghrelin/GHS[edit]
- See here instead.
GH[edit]
- See here instead.
GHRH[edit]
- See here instead.
GLP[edit]
GLP-1[edit]
- Agonists: Albiglutide
- Beinaglutide
- Dulaglutide
- Efpeglenatide
- Exenatide
- GLP-1
- Langlenatide
- Liraglutide
- Lixisenatide
- Oxyntomodulin
- Pegapamodutide
- Semaglutide
- Taspoglutide
GLP-2[edit]
- Agonists: Apraglutide
- Elsiglutide
- Glepaglutide
- GLP-2
- Teduglutide
Others[edit]
- Propeptides: Preproglucagon
- Proglucagon
Glucagon[edit]
- Agonists: Dasiglucagon
- Glucagon
- Oxyntomodulin
- Antagonists: Adomeglivant
- L-168,049
- LGD-6972
- Propeptides: Preproglucagon
- Proglucagon
GnRH[edit]
- See here instead.
Gonadotropin[edit]
- See here instead.
Growth factor[edit]
- See here instead.
Insulin[edit]
- Agonists: Chaetochromin (4548-G05)
- Insulin-like growth factor 1
- Insulin-like growth factor 2
- Insulin
- Insulin aspart
- Insulin degludec
- Insulin detemir
- Insulin glargine
- Insulin glulisine
- Insulin lispro
- Mecasermin
- Mecasermin rinfabate
- Antagonists: BMS-754807
- S661
- S961
- Kinase inhibitors: Linsitinib
- Antibodies: Xentuzumab (against IGF-1 and IGF-2)
Kisspeptin[edit]
- Agonists: Kisspeptin
- Kisspeptin-10
- Antagonists: Kisspeptin-234
Leptin[edit]
- Agonists: Leptin
- Metreleptin
Melanin-concentrating hormone receptor[edit]
MCH1[edit]
- Agonists: Melanin-concentrating hormone
MCH2[edit]
- Agonists: Melanin-concentrating hormone
Melanocortin[edit]
- See here instead.
mTOR[edit]
- Inhibitors: Rapalogs: Everolimus
- Ridaforolimus
- Sirolimus (Rapamycin)
- Temsirolimus
- Umirolimus
- Zotarolimus; ATP-competitive / indirect: Berberine
- Curcumin
- Dactolisib
- EF-24
- Epigallocatechin gallate
- HY-124798
- NV-5440
- Pterostilbene
- Quercetin
- Resveratrol
- Sapanisertib
- Torin-1
- WYE-687
- XL-388
Neuropeptide FF[edit]
Neuropeptide S[edit]
- Agonists: Neuropeptide S
Neuropeptide Y[edit]
Y1[edit]
- Agonists: Neuropeptide Y
- Peptide YY
Y2[edit]
- Agonists: 2-Thiouridine 5'-triphosphate
- Neuropeptide Y
- Neuropeptide Y (13-36)
- Peptide YY
- Peptide YY (3-36)
- Antagonists: BIIE-0246
- JNJ-5207787
- SF-11
Y4[edit]
- Antagonists: UR-AK49
Y5[edit]
- Agonists: BWX-46
- Neuropeptide Y
- Peptide YY
- Antagonists: CGP-71683
- FMS-586
- L-152,804
- Lu AA-33810
- MK-0557
- NTNCB
- Velneperit (S-2367)
Neurotensin[edit]
NTS1[edit]
- Agonists:
- Antagonists:
NTS2[edit]
- Agonists:
- Antagonists:
Opioid[edit]
- See here instead.
Orexin[edit]
OX1[edit]
- Antagonists: ACT-335827
- ACT-462206
- Almorexant
- Filorexant
- Lemborexant
- Nemorexant
- RTIOX-276
- SB-334867
- SB-408124
- SB-649868
- Suvorexant
- TCS-1102
OX2[edit]
- Antagonists: ACT-335827
- ACT-462206
- Almorexant
- EMPA
- Filorexant
- JNJ-10397049
- Lemborexant
- MK-1064
- SB-649868
- Seltorexant
- Suvorexant
- TCS-1102
- TCS-OX2-29
Oxytocin[edit]
- See here instead.
Prolactin[edit]
- Agonists: Growth hormone
- Human placental lactogen
- Placental growth hormone (growth hormone variant)
- Prolactin
- S179D-hPRL
- Somatotropin
- Antagonists: Δ1–9-G129R-hPRL
- Δ1–14-G129R-hPRL
- G120K-hGH
- G129R-hPRL
- Prolactin modulators: Prolactin inhibitors: D2 receptor agonists (e.g., bromocriptine, cabergoline); Prolactin releasers: D2 receptor antagonists (e.g., domperidone, metoclopramide, risperidone)
- Estrogens (e.g., estradiol)
- Progestogens (e.g., progesterone)
PTH[edit]
- Agonists: Abaloparatide
- Parathyroid hormone
- Parathyroid hormone-related protein (PTHrP)
- Semparatide
- Teriparatide
Relaxin[edit]
Somatostatin[edit]
- See here instead.
Tachykinin[edit]
- See here instead.
TRH[edit]
- Agonists: Azetirelin
- Fertirelin
- Montirelin
- Orotirelin
- Posatirelin
- Protirelin
- Rovatirelin
- Taltirelin
- TRH (TRF)
TSH[edit]
- Agonists: Thyrotropin alfa
- TSH (thyrotropin)
Vasopressin[edit]
- See here instead.
VIP/PACAP[edit]
VIPR1[edit]
- Agonists: Peptide: Bay 55-9837
- LBT-3393
- PACAP
- VIP
VIPR2[edit]
PAC1[edit]
- Agonists: PACAP
- PACAP (1-27)
- PACAP (1-38)
- Antagonists: PACAP (6-38)
Unsorted[edit]
Others[edit]
- Endogenous: Adrenomedullin
- Apelin
- Asprosin
- Bombesin
- Calcitonin
- Carnosine
- CART
- CLIP
- DSIP
- Enteroglucagon
- Formyl peptide
- GALP
- GIP
- GRP
- Integrin ligands (collagens, fibrinogen, fibronectin, laminins, ICAM-1, ICAM-2, osteopontin, VCAM-1, vitronectin)
- Kininogens
- Motilin
- Natriuretic peptides (ANP, BNP, CNP, urodilatin)
- Nesfatin-1
- Neuromedin B
- Neuromedin N
- Neuromedin S
- Neuromedin U
- Obestatin
- Osteocalcin
- Resistin
- Secretin
- Thymopoietin
- Thymosins
- Thymulin
- Urotensin-II
- VGF
- Exogenous: Lifitegrast (LFA-1 antagonist)
References[edit]
- ^ Sigma-Aldrich Solutions. "Neurotensin Receptors". Merck. Retrieved 20 October 2021.