Leucine N-acetyltransferase
| leucine N-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.66 | ||||||||
| CAS no. | 75496-56-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a leucine N-acetyltransferase (EC 2.3.1.66) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + L-leucine CoA + N-acetyl-L-leucine
Thus, the two substrates of this enzyme are acetyl-CoA and L-leucine, whereas its two products are CoA and N-acetyl-L-leucine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-leucine N-acetyltransferase. This enzyme is also called leucine acetyltransferase.
References[edit]
- Suzukake S, Hayashi H, Hori M, Umezawa H (1982). "Biosnthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine". J. Antibiot. 33 (8): 857–862. doi:10.7164/antibiotics.33.857. PMID 7429989.
