Hélène Bergès

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Hélène Bergès
Born (1966-08-27) 27 August 1966 (age 57)
Pau, France
NationalityFrench
Alma materUniversity of Toulouse III
Awards
  • IWGSC Leadership Award (2019)
  • Vermeil Medal of French Academy of Agriculture (2015)
  • Legion of Honor (2015)
  • Order of Agricultural Merit (2013)
Scientific career
FieldsGenomics
ThesisEtude de l'export de protéïnes hétérologues chez la bactérie Escherichia coli (1995)

Hélène Bergès (born August 27, 1966 in Pau) is a French scientist and was the Director of the French Plant Genomic Resources Center from its foundation until 2019.

Education[edit]

Bergès completed a doctorate in 1995 at the Toulouse III - Paul Sabatier University in the fields of genetics and molecular biology.[1]

Career[edit]

After her PhD, Bergès joined the National Institute for Agricultural Research (INRA) in 1998, to first focus on research in studying plant interactions with microbes. In 2003, her position at INRA allowed her to found a separate department called the French Plant Genomic Resources Center (CNRGV) where she was the director until 2019.[1] Employing some twenty people, the CNRGV is involved in various international sequencing consortia, develops various projects funded by the French Government (Grand Emprunt), the French National Research Agency (ANR) or the European Union, in collaboration with various laboratories all around the world.[citation needed] Along other activities, Hélène Bergès is member of the scientific committee of the Parliamentary Office for the Evaluation of Scientific and Technological Options (OPECST).[1] In 2021, she was one of the researchers highlighted in the " La Science taille XX elles" exhibition presented in Toulouse.[2]

Research[edit]

Bergès' early research used Escherichia coli as a model system to examine cytokines[3] and plasmid copy numbers.[4] She then she moved on to examine the bacterial cells associated with plant roots including the development of microarrays[5] which allowed her to quantify gene expression in these bacteria.[6][7] She was an early adopter of the need to sequence plant genomes,[8] and her recent work includes large-scale sequencing projects including those generating genomic information on barley,[9] wheat,[10] and sunflowers.[11]

Selected publications[edit]

Awards and honors[edit]

The National Institute for Agricultural Research gave Bergès their 2012 engineering award.[12] She was one of ten recipients of the 2015 Vermeil Medal of the French Academy of Agriculture,[13] and she was given the 2018 "Outstanding Leadership Award" from the International Wheat Genome Sequencing Consortium, for "her leadership in BAC pooling and BAC libraries".[14] In 2015, she was made Knight of Legion of Honour,[15] and she is also a Knight of the Order of Agricultural Merit.

References[edit]

  1. ^ a b c "Helene Bergès: Genomicist". cnrs.fr. French National Centre for Scientific Research. 2021. Retrieved January 8, 2022.
  2. ^ "Hélène Bergès | CNRS". www.cnrs.fr (in French). November 17, 2021. Retrieved 2022-01-08.
  3. ^ Bergès, H; Joseph-Liauzun, E; Fayet, O (January 1996). "Combined effects of the signal sequence and the major chaperone proteins on the export of human cytokines in Escherichia coli". Applied and Environmental Microbiology. 62 (1): 55–60. doi:10.1128/aem.62.1.55-60.1996. PMC 167772. PMID 8572712.
  4. ^ Bergès, H; Oreglia, J; Joseph-Liauzun, E; Fayet, O (February 1997). "Isolation and characterization of a priB mutant of Escherichia coli influencing plasmid copy number of delta rop ColE1-type plasmids". Journal of Bacteriology. 179 (3): 956–958. doi:10.1128/jb.179.3.956-958.1997. PMC 178782. PMID 9006055.
  5. ^ Bergès, Hélène; Lauber, Emmanuelle; Liebe, Carine; Batut, Jacques; Kahn, Daniel; Bruijn, Frans J. de; Ampe, Frédéric (2003). "Development of Sinorhizobium meliloti Pilot Macroarrays for Transcriptome Analysis". Applied and Environmental Microbiology. 69 (2): 1214–1219. doi:10.1128/AEM.69.2.1214-1219.2003. PMC 143623. PMID 12571049.
  6. ^ Becker, Anke; Bergès, Hélène; Krol, Elizaveta; Bruand, Claude; Rüberg, Silvia; Capela, Delphine; et al. (1 March 2004). "Global Changes in Gene Expression in Sinorhizobium meliloti 1021 under Microoxic and Symbiotic Conditions". Molecular Plant-Microbe Interactions. 17 (3): 292–303. doi:10.1094/MPMI.2004.17.3.292. ISSN 0894-0282. PMID 15000396.
  7. ^ Bergès, Hélène; Checroun, Claire; Guiral, Sébastien; Garnerone, Anne-Marie; Boistard, Pierre; Batut, Jacques (2001). "A glutamine-amidotransferase-like protein modulates FixT anti-kinase activity in Sinorhizobium meliloti". BMC Microbiology. 1 (1): 6. doi:10.1186/1471-2180-1-6. PMC 32199. PMID 11389771.
  8. ^ "Toulouse. Guérir des maladies grâce à l'ADN de la tomate". ladepeche.fr (in French). October 4, 2012. Retrieved 2022-01-08.
  9. ^ "A physical, genetic and functional sequence assembly of the barley genome". Nature. 491 (7426): 711–716. November 2012. doi:10.1038/nature11543. hdl:2440/76951. S2CID 10170672.
  10. ^ Paux, Etienne; Sourdille, Pierre; Salse, Jérôme; Saintenac, Cyrille; Choulet, Frédéric; Leroy, Philippe; et al. (3 October 2008). "A Physical Map of the 1-Gigabase Bread Wheat Chromosome 3B". Science. 322 (5898): 101–104. doi:10.1126/science.1161847. PMID 18832645. S2CID 27686615.
  11. ^ Badouin, Hélène; Gouzy, Jérôme; Grassa, Christopher J.; Murat, Florent; Staton, S. Evan; Cottret, Ludovic; et al. (June 2017). "The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution". Nature. 546 (7656): 148–152. doi:10.1038/nature22380. hdl:1828/12772. PMID 28538728. S2CID 4467404.
  12. ^ "Hélène Bergès, le génome de sa vie" [Hélène Bergès, the genome of her life]. echosciences-sud.fr (in French). Echosciences Occitanie. January 29, 2018. Retrieved January 8, 2022.
  13. ^ "Médaille de VERMEIL de l'Académie". academie-agriculture.fr. French Academy of Agriculture. 2015. Retrieved January 8, 2022.
  14. ^ "Hélène Bergès". 2018 Awardees. International Wheat Genome Sequencing Consortium. February 8, 2019.
  15. ^ "Légion d'honneur : Pierre Soulages grand croix, Sinclair et Bel chevaliers, Enders commandeur" [Legion of Honor: Pierre Soulages Grand Croix, Sinclair and Bel Chevaliers, Enders Commander]. La Dépêche du Midi (in French). June 4, 2015. Retrieved January 8, 2022.

Further reading[edit]

External links[edit]

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