Mannosulfan

Mannosulfan
Clinical data
Other names	[(2R,3S,4S,5R)-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate
ATC code	L01AB03 (WHO) ;
Identifiers
	IUPAC name 1,2,5,6-Tetrakis-O-(methylsulfonyl)-D-mannitol;
CAS Number	7518-35-6 ;
PubChem CID	24140;
ChemSpider	16736959;
UNII	135FQ40L36;
Chemical and physical data
Formula	C10H22O14S4
Molar mass	494.51 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C;
	InChI InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1; Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N;
	(verify)

Mannosulfan (INN) is an alkylating agent with the potential for the treatment of cancer. It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonate Busulfan.^[1]

References

^ Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp. 281–98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBN 978-0-323-52727-9.

External links

Media related to Mannosulfan at Wikimedia Commons

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[1] Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp. 281–98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBN 978-0-323-52727-9.

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