APSC
APSC may refer to:
- APSC Pariyaram, the Academy of Pharmaceutical Sciences, Pariyaram
- APS-C, the Advanced Photo System type-C image sensor format
- The African People's Solidarity Committee, a committee of the African People's Socialist Party
- Alaska Police Standards Council
- The Arkansas Public Service Commission
- The Australian Public Service Commission
- The Association of Southeast Asian Nations Political-Security Community
- The Assam Public Service Commission
- The Army Public School, Chennai, a public school in Chennai, India