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Protein-coding gene in the species Homo sapiens
Apoptotic chromatin condensation inducer in the nucleus is a protein that in humans is encoded by the ACIN1 gene .[5] [6] [7]
References [ edit ]
^ a b c GRCh38: Ensembl release 89: ENSG00000100813 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022185 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" . DNA Res . 5 (3): 169–76. doi :10.1093/dnares/5.3.169 PMID 9734811 . ^ Sahara S, Aoto M, Eguchi Y, Imamoto N, Yoneda Y, Tsujimoto Y (Sep 1999). "Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation". Nature . 401 (6749): 168–73. Bibcode :1999Natur.401..168S . doi :10.1038/43678 . PMID 10490026 . S2CID 4364282 . ^ "Entrez Gene: ACIN1 apoptotic chromatin condensation inducer 1" .
External links [ edit ] Further reading [ edit ]
Zermati Y, Garrido C, Amsellem S, et al. (2001). "Caspase activation is required for terminal erythroid differentiation" . J. Exp. Med . 193 (2): 247–54. doi :10.1084/jem.193.2.247 . PMC 2193347 PMID 11208865 . Sordet O, Rébé C, Plenchette S, et al. (2003). "Specific involvement of caspases in the differentiation of monocytes into macrophages" . Blood . 100 (13): 4446–53. doi :10.1182/blood-2002-06-1778 PMID 12393560 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Shu H, Chen S, Bi Q, et al. (2004). "Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line" . Mol. Cell. Proteomics . 3 (3): 279–86. doi :10.1074/mcp.D300003-MCP200 PMID 14729942 . Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5. Bibcode :2004PNAS..10112130B . doi :10.1073/pnas.0404720101 PMC 514446 PMID 15302935 . Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" . Curr. Biol . 14 (16): 1436–50. doi :10.1016/j.cub.2004.07.051 PMID 15324660 . S2CID 2371325 . Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res . 4 (4): 1339–46. doi :10.1021/pr050048h . PMID 16083285 . Hu Y, Yao J, Liu Z, et al. (2005). "Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation" . EMBO J . 24 (20): 3543–54. doi :10.1038/sj.emboj.7600823 . PMC 1276706 PMID 16177823 . Joselin AP, Schulze-Osthoff K, Schwerk C (2006). "Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis" . J. Biol. Chem . 281 (18): 12475–84. doi :10.1074/jbc.M509859200 PMID 16537548 . Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol . 24 (10): 1285–92. doi :10.1038/nbt1240 . PMID 16964243 . S2CID 14294292 . Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . Shu Y, Iijima T, Sun W, et al. (2007). "The ACIN1 gene is hypermethylated in early stage lung adenocarcinoma". Journal of Thoracic Oncology . 1 (2): 160–7. doi :10.1097/01243894-200602000-00010 . PMID 17409846 .
