2-dehydro-3-deoxy-L-arabinonate dehydratase
| 2-dehydro-3-deoxy-L-arabinonate dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.43 | ||||||||
| CAS no. | 37263-10-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) catalyzes the chemical reaction
- 2-dehydro-3-deoxy-L-arabinonate 2,5-dioxopentanoate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming). Other names in common use include 2-keto-3-deoxy-L-arabinonate dehydratase, and 2-dehydro-3-deoxy-L-arabinonate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.
References[edit]
- Stoolmiller AC, Abeles RH (1966). "Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila". J. Biol. Chem. 241 (24): 5764–71. PMID 5954356.
