(deoxy)adenylate kinase
| (deoxy)adenylate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.4.11 | ||||||||
| CAS no. | 37278-19-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a (deoxy)adenylate kinase (EC 2.7.4.11) is an enzyme that catalyzes the chemical reaction
- ATP + dAMP ADP + dADP
Thus, the two substrates of this enzyme are ATP and dAMP, whereas its two products are ADP and dADP.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)AMP phosphotransferase. This enzyme participates in purine metabolism.
References[edit]
- Griffith TJ, Helleiner CW (1965). "The partial purification of deoxynucleoside monophosphate kinases from L cells". Biochim. Biophys. Acta. 108 (1): 114–24. doi:10.1016/0005-2787(65)90113-9. PMID 5862227.
