(+)-car-3-ene synthase

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(+)-car-3-ene synthase
Identifiers
EC no.4.2.3.107
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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(+)-Car-3-ene synthase (EC 4.2.3.107, 3-carene cyclase, 3-carene synthase, 3CAR, (+)-3-carene synthase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-car-3-ene-forming].[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

geranyl diphosphate (+)-car-3-ene + diphosphate

The enzyme reacts with (3S)-linalyl diphosphate twice as rapidly as geranyl diphosphate.

References[edit]

  1. ^ Savage TJ, Croteau R (September 1993). "Biosynthesis of monoterpenes: regio- and stereochemistry of (+)-3-carene biosynthesis". Archives of Biochemistry and Biophysics. 305 (2): 581–7. doi:10.1006/abbi.1993.1464. PMID 8373196.
  2. ^ Savage TJ, Ichii H, Hume SD, Little DB, Croteau R (July 1995). "Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents". Archives of Biochemistry and Biophysics. 320 (2): 257–65. doi:10.1016/0003-9861(95)90008-x. PMID 7625832.
  3. ^ Savage TJ, Hatch MW, Croteau R (February 1994). "Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase". The Journal of Biological Chemistry. 269 (6): 4012–20. doi:10.1016/S0021-9258(17)41735-2. PMID 8307957.
  4. ^ Fäldt J, Martin D, Miller B, Rawat S, Bohlmann J (January 2003). "Traumatic resin defense in Norway spruce (Picea abies): methyl jasmonate-induced terpene synthase gene expression, and cDNA cloning and functional characterization of (+)-3-carene synthase". Plant Molecular Biology. 51 (1): 119–33. doi:10.1023/A:1020714403780. PMID 12602896. S2CID 21153303.
  5. ^ Hamberger B, Hall D, Yuen M, Oddy C, Hamberger B, Keeling CI, Ritland C, Ritland K, Bohlmann J (August 2009). "Targeted isolation, sequence assembly and characterization of two white spruce (Picea glauca) BAC clones for terpenoid synthase and cytochrome P450 genes involved in conifer defence reveal insights into a conifer genome". BMC Plant Biology. 9: 106. doi:10.1186/1471-2229-9-106. PMC 2729077. PMID 19656416.
  6. ^ Hall DE, Robert JA, Keeling CI, Domanski D, Quesada AL, Jancsik S, Kuzyk MA, Hamberger B, Borchers CH, Bohlmann J (March 2011). "An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil". The Plant Journal. 65 (6): 936–48. doi:10.1111/j.1365-313x.2010.04478.x. PMID 21323772.

External links[edit]