User:Tony Mach/Pituitary

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The hormones of the pituitary effect several organs in the body, as such, over- or underproduction of these hormones can affect the end organs in the hypothalamic–pituitary–adrenal axis, hypothalamic–pituitary–gonadal axis or hypothalamic–pituitary–thyroid axis.

Axis	Results of pituitary hyposecretion	Results of pituitary hypersecretion
HPA /Adrenal	Secondary hypocortisolism Sheehan's syndrome	Secondary hypercortisolism Cushing's disease, Pseudo-Cushing's syndrome
HPT / Thyroid	Secondary hypothyroidism	Hyperthyroidism
HPG / Gonads	Example	Example
Growth / IGF-1	Example	Example
Prolactin (PRL)	Example	Example
Vasopressin (AVP) (Antidiuretic hormone, ADH)	Diabetes insipidus hypernatremia (increased blood sodium concentration), polyuria (excess urine production), and polydipsia (thirst)	Vasopressin#Excess_AVP Syndrome of inappropriate antidiuretic hormone hypersecretion (SIADH)
Oxytocin (OXT)	Example	Example

*Hypothalamic-pituitary-end organ axis*
	HPT	HPA	HPG	Growth	Breast
Releasing hormone	TRH	CRH	GnRH	GHRH	Dopamine (inhibitor)
Pituitary cells	Thyrotrope	Corticotrope	Gonadotrope	Somatotrope	Lactotrope
Pituitary hormone	TSH	ACTH	LH and FSH	GH	Prolactin
End organ	Thyroid	Adrenal	Gonads (Testes or ovaries)	Liver	Breast gland
Product	Thyroxine	Cortisol	Testosterone or estradiol	IGF-1	Milk (no feedback)

References[edit]