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Virgil Percec
Born
Virgil Percec

(1946-12-08) December 8, 1946 (age 77)
Academic background
EducationPolytechnic University in Iasi
(BA, 1969; PhD, 1976)
Academic work
Institutions
WebsiteProfessor Virgil Percec

Virgil Percec (born December 8, 1946)[1] is a Romanian-American chemist and P. Roy Vagelos Chair and Professor of Chemistry at the University of Pennsylvania. Expert in organic, macromolecular and supramolecular chemistry including self-assembly, biological membrane mimics, complex chiral systems, and catalysis. Pioneered the fields of liquid crystals with complex architecture[2], supramolecular dendrimers, Janus dendrimers and glycodendrimers, organic Frank-Kasper phases and quasicrystals, supramolecular polymers, helical chirality, Ni-catalyzed cross-coupling and multiple living and self-interrupted polymerizations. Most of these concepts were inspired by Nature and biological principles.

Life[edit]

Early Life[edit]

Virgil Percec was born on December 1946 in Siret, Romania. His parents were Traian and Virginia Percec. Traian was a schoolteacher and a talented painter. Virgil attended the elementary and high school Eudoxius Hurmuzachi in Radauti, one of the oldest institutions of education established in 1872 in Bucovina .The school was named after Eudoxius Hurmuzachi, a member of the Romanian Academy, who campaigned for the rights of Romanians in the Habsburg Empire.

Education[edit]

Percec received his BS in Organic and Macromolecular Chemistry at the Polytechnic University in Iasi in 1969 and his PhD in 1976 at the Institute of Macromolecular Chemistry in Iasi[3] where he had Cristofor Simionescu as a mentor. In 1981 he defected his native country and after short postdoctoral stays at the University of Freiburg in Germany (July 1981 with H. -J. Cantow) and University of Akron, US (August 1981 to March 1982 with J. P. Kennedy) he joined the Department of Macromolecular Science of Case Western Reserve University (CWRU) in Cleveland, US in March 1982 as an Assistant Professor. He was promoted to Associate Professor in 1984 and to Professor in 1986. In 1991 he became director of Materials Research Science and Engineering Centers (MRSEC) and in 1993, he was awarded the Leonard Case Jr. Chair at CWRU. In 1999 he moved to the University of Pennsylvania in Philadelphia as P. Roy Vagelos Chair and Professor of Chemistry. He has been repeatedly a Visiting Professor at the Universities of Freiburg, Ulm and at the Max Planck Institute for Polymer Research in Mainz (all in Germany) and at the Royal Institute of Technology in Stockholm, Sweden.

Personal Life[edit]

Percec and his wife, Simona have a daughter Ivona Percec.[4] She earned a double major from Princeton University and received an MD/PhD from University of Pennsylvania where she joined the faculty and surgery department.

Research[edit]

Percec has made scientific contributions in diverse areas, including the discovery of all helical stereoisomers of polyphenylacetylene, their interconversion and intramolecular electrocyclization with applications in chiral separation, sensors, membranes, molecular machines[5], the discovery of liquid crystals based on conformational isomerism: polyethers, poly(vinyl ether)s, macrocyclics, covalent and supramolecular dendrimers[6][7][8] the discovery of self-assembling dendrons, dendrimers and dendronized polymers; and the creation of helical rod-like and spherical viruses mimics. He generated the first organic Frank-Kasper phases and quasicrystals.[9][10][11][12] He revealed double-helices disregarding chirality and deracemization in crystal state, designed the sequence-rearrangement concept to transform dynamic racemic (atactic) into homochiral (isotactic) supramolecular polymers[13] and demonstrated acceleration of self-assembly and disassembly by fluorine and fluorous phase.[14] His discovery of self-interrupted and self-accelerated iterative organic synthesis, polymerizations and living polymerizations produced the first monodisperse polymers by noniterative synthesis.[15] More recently, he uncovered biological membrane mimics from Janus dendrimers, glycodendrimers and ionizable dendrimers; determined they self-assemble into monodisperse artificial cell-like mimics, co-assemble with bacterial and human cells, and generate one component mRNA delivery systems for virus vaccines and drugs.[16] He is also known for the methodologies he developed for organic, macromolecular and supramolecular synthesis: replacement of Pd with Ni in cross-coupling reactions, the concepts of mixed-ligands and catalytic solvents, phase-transfer catalyzed living condensation polymerization, new mechanisms for living polymerization of acetylenes, single-electron-transfer mediated organic and polymerization reactions including living polymerizations.[17][18]

Awards and achievements[edit]

Percec is the author of more than 800 scientific articles, 20 books and special issues and listed as inventor of at least 80 patents. Percec presented over 1200 endowed, plenary and invited lectures. He has served as the Editor of Journal of Polymer Science: Part A: Polymer Chemistry, Advances in Polymer Science and Book Series “Liquid Crystals”. He serves on Editorial and Advisory Scientific Boards of 23 International Journals, and of the advisory boards of many Academic and Industrial Institutions. Percec is a member of foreign Academies, received US and international awards, organized numerous International Symposia and educated over 300 PhD and postdoctoral students with more than 70 of them being in faculty positions.

Awards[edit]

References[edit]

  1. ^ https://web.sas.upenn.edu/percecgroup/professor-percec/
  2. ^ https://www.sas.upenn.edu/sasalum/newsltr/fall05/SASMagFa05_webfinb.pdf
  3. ^ https://icmpp.ro
  4. ^ https://www.pennmedicine.org/cosmetic-services/meet-the-team/meet-the-doctors/ivona-percec
  5. ^ https://onlinelibrary.wiley.com/doi/pdf/10.1002/pol.1977.170151018
  6. ^ https://science.sciencemag.org/content/278/5337/449/tab-pdf
  7. ^ https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852099
  8. ^ https://www.nature.com/articles/34384.pdf
  9. ^ https://www.nature.com/articles/34384.pdf
  10. ^ https://science.sciencemag.org/content/299/5610/1208/tab-pdf
  11. ^ https://www.nature.com/articles/nature02368.pdf
  12. ^ https://www.nature.com/articles/nature02770.pdf
  13. ^ https://pubs.acs.org/doi/pdf/10.1021/ja8094944
  14. ^ https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852099
  15. ^ https://pubs.acs.org/doi/pdf/10.1021/jacs.0c07912
  16. ^ https://science.sciencemag.org/content/328/5981/1009/tab-pdf
  17. ^ https://pubs.acs.org/doi/pdf/10.1021/cr100259t
  18. ^ https://pubs.acs.org/doi/pdf/10.1021/ja065484z
  19. ^ https://clarivate.com/news/global-highly-cited-researchers-2018-list-reveals-influential-scientific-researchers-and-their-institutions/#:~:text=Top%2010%20lists%20from%202018%20HCR%20%20,Sciences,%20China%20(99)%20%206%20more%20rows%20
  20. ^ https://in.bgu.ac.il/en/natural_science/Pages/default.aspx
  21. ^ https://www.acs.org/content/acs/en/global/international/chapters/romania.html
  22. ^ http://www.schr.ro/
  23. ^ https://cen.acs.org/sponsored-content/acs-kavli-lectures.html
  24. ^ https://www.chemistry.org.il/
  25. ^ https://www.ofi.at
  26. ^ https://scg.ch/
  27. ^ https://www.ptn.nu/ptn/