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Pharmacoengineering is a portmanteau for pharmaceutical science and engineering (e.g., Biomedical or Chemical Engineering). This area of research is focused on drug delivery and pharmaceutics with a significant medical or translational application. The overall goal of this area of research is to optimally engineer delivery of a pharmaceutical over time (e.g. controlled release) and at the area of the body where the pharmaceutical is most needed (e.g. targeted drug delivery), in an effort to reduce off-target toxicity (e.g. drug side-effects). It employs concepts such nanoparticles (e.g. liposomes, micelles), microparticles (e.g. biodegradable polymer particles), biodegradable polymer scaffolds[1], biologics, stem cells[1], vaccines (prophylactic and therapeutic), and gene therapy.
The term was first reported by UNC Eshelman School of Pharmacy and joint University of North Carolina/North Carolina State University Department of Biomedical Engineering[2]. The term has been increasing used to describe academic units, such as the Division of Pharmacoengineering and Molecular Pharmaceutics in the UNC Eshelman School of Pharmacy[3], and academic research labs[4][5].
- ^ a b "Pharmacoengineering". Radio In Vivo. Retrieved 25 July 2018.
- ^ "UNC Research Opportunities Initiative". University of North Carolina System. Retrieved 25 July 2018.
- ^ "UNC Division of Pharmacoengineering and Molecular Pharmaceutics (DPMP)". Nature Index. Retrieved 25 July 2018.
- ^ "Pharmacoengineering Labortory". Retrieved 25 July 2018.
- ^ "Laboratory of Molecular Pharmacoengineering". Retrieved 25 July 2018.