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User:Rebeccachappel/sandbox

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About

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My name is Rebecca Chappel and I am in my first semester of the MS Bioinformatics program at Johns Hopkins. I received a BS in Chemistry in 2007. After working for a few years in genomic sequencing research I confirmed my interest in the bioinformatics field and I'm excited to be starting my degree. Outside of class, my main hobbies are cooking and photography. Inside of class, my main interests are genetic sequencing and using that data in clinical settings diagnostically.


Five Pillars of Wikipedia[1]

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Number 1

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Wikipedia is a source of information, not advertising or a place for people’s personal views on different issues.

Number 2

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Wikipedia is neutral and has an aim to just report facts. If there are multiple points of view, each point will try to be represented neutrally. Material that does not have adequate references or are opinion based can be removed.

Number 3

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Wikipedia is free to the public both for use and modification.

Number 4

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Collaboration is key. There is an etiquette for collaborating with Wikipedia editors.

Number 5

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Wikipedia is not static. Rules and articles are subject to change. The site exists and benefits from people being bold enough to make changes.


Summary of Characteristics of Target Article[2]

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GA, Good Article Class Article

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  • Well written article
  • All references listed and sources of information sited
  • Extensive coverage of subject
  • Neutral viewpoint without any bias
  • Supporting materials including images containing suitable references and captions

B Class Article

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  • Article mostly complete with no major issues
  • Referenced with reliable sources
  • Contains enough information to suitably cover subject
  • Defined structure
  • Supporting materials if necessary


Practice Citing Sources

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BRCA1 is the breast cancer susceptibility gene 1. Mutations in this gene increase the risk of breast cancer.[3] Approximately 40-45% of hereditary breast cancer is linked to BRCA1.[4] The BRCA1 protein is involved in DNA repair which an important part of tumorigensis.[3] The research done involving BRCA1 and BRCA2 and its relation to breast cancer lead to the creation of CIMBA (Consortium of Investigators of Modifier of BRCA1 and BRCA2). [5]


References

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  1. ^ "Wikipedia:Training: Five pillars". Wikipedia Training.
  2. ^ "Wikipedia:Quality: Grades". Wikipedia.
  3. ^ a b Cox, D. G.; et al. (2011 Dec 1). "Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers". Human Molecular Genetics. 20 (23): 4732–47. doi:10.1093/hmg/ddr388. PMC 3733139. PMID 21890493. {{cite journal}}: |author26= has generic name (help); Check date values in: |date= (help)
  4. ^ Dever, S. M.; White, E. R.; Hartman, M. C.; Valerie, K. (2012 Feb 15). "BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies". Cell Cycle (Georgetown, Tex.). 11 (4): 687–94. doi:10.4161/cc.11.4.19212. PMC 3318103. PMID 22306997. {{cite journal}}: Check date values in: |date= (help)
  5. ^ Chenevix-Trench, G.; Milne, R. L.; Antoniou, A. C.; Couch, F. J.; Easton, D. F.; Goldgar, D. E.; CIMBA (2007). "An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)". Breast Cancer Research : BCR. 9 (2): 104. doi:10.1186/bcr1670. PMC 1868919. PMID 17466083.{{cite journal}}: CS1 maint: unflagged free DOI (link)