Antonio de Montesinos – lived in Hispaniola, spoke against treatment of slaves and indigenous populations
San Miguel de Gualdape (1526) – unsuccessful colony in present-day South Carolina (later moved to Georgia), lasted less than 3 months, 150 survived of original 600
first European settlement in present-day US
first slave revolt in mainland North America
Juan Ortiz (captive) – held captive in Florida from 1528 to 1539, spared from burning alive by chief's daughter
De Soto expedition (1541) – 620 men + 220 horses, into mainland southeast US, crossing Mississippi, clashing with many tribes, searching for gold
captured Natives from tribes for translation and slave labor
raided villages for food and sex slaves
battled Timucuan groups, executed 200 in Napituca Massacre
ambushed during 9-hour battle at Mabila, 200 Spaniards killed, 2,500–3,000 inhabitants killed and village burned
Chickasaw ambushed them at night, killed 40 Spaniards
clashed with Tula, most dangerous and skilled warriors
rowed 7 boats down Mississippi, encountering hostile fleets of war canoes along the entire course, notably the Quigualtam shooting at them for days on end, 11 Spaniards killed
sailed down Gulf of Mexico to Pánuco for rest, then to Mexico City, ~300 had survived, most stayed in the New World