User:M2bioinfo-Orsay/sandbox/team3

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Riboswitch s0670[edit]

Riboswitch s0670 family
Predicted secondary structure using RSCape[1]
Identifiers
Other data
RNA typeGene; Cis-reg; riboswitch;
Domain(s)Bacteria; Firmicutes
PDB structuresPDBe

The s0670 family was defined with the rfam cloud pipeline from the CD630_s0670 nucleotide sequence which is a non-coding RNA of the pathogenic bacteria Clostridium difficile 630 revealed by RNA-seq and differential 5'-and RNA-seq analyses[2].

RNA of this family were found in the Firmicutes taxa and upstream of some genes which code for enzyme implicated in cellular amino acid metabolic process (GO:0006520) like the O-acetylhomoserine sulfhydrylase of Clostridium difficile (FQTY01000002.1 ⇒ en 5’ d’un gène O-acetylhomoserine sulfhydrylase SHE43394.1), the S-ribosylhomocysteinase LuxS of ?? (DS995361.1 ⇒ en 5’ du gène EEA84185.1), or the cysD gene of ?? (FMDO01000052.1 ⇒ en 5’ du gène SCG84166.1).

The seconday structure was predicted using the locaRNA[3] alignement and with the Rscape prediction software[1].

References[edit]

  1. ^ a b "Estimating the power of sequence covariation for detecting conserved RNA structure". Bioinformatics. 36 (10): 3072–3076. 2020. doi:10.1093/bioinformatics/btaa080. {{cite journal}}: Cite uses deprecated parameter |authors= (help)
  2. ^ "Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile". PLoS Genet. 9 (5): e1003493. 2013. doi:10.1371/journal.pgen.1003493. PMID 23675309. {{cite journal}}: Cite uses deprecated parameter |authors= (help)CS1 maint: unflagged free DOI (link)
  3. ^ "LocARNA-P: Accurate boundary prediction and improved detection of structural RNAs". RNA. 18 (5): 900–914. 2012. doi:10.1261/rna.029041.111. {{cite journal}}: Cite uses deprecated parameter |authors= (help)

Category:Non-coding RNA