User:Cheungn/sandbox

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Under list of monoclonal antibodies. http://en.wikipedia.org/wiki/List_of_monoclonal_antibodies

antibody 8H9 binds to target B7-H3, use for radioimmunotherapy of brain metastasis

references: B7-H3:

Xu H, Cheung IY, Guo HF, Cheung NK. MicroRNA miR-29 Modulates Expression of Immunoinhibitory Molecule B7-H3: Potential Implications for Immune Based Therapy of Human Solid Tumors. Cancer Research 69:6275-6281, 2009

Radioimmunotherapy of Brain metastasis

Kramer K, Kushner BH, Modak S, Pandit-Taskar N, Smith-Jones P, Zanzonico P, Humm JL, Xu H, Wolden SL, Souweidane MM, Larson SM, Cheung NK. Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma. Journal of Neurooncology, 97:409-418, 2010.