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The superior temporal sulcus (STS) is the sulcus separating the superior temporal gyrus from the middle temporal gyrus in the temporal lobe of the brain. A sulcus (plural sulci) is a deep groove that curves into the largest part of the brain, the cerebrum, and a gyrus (plural gyri) is the a ridge that curves outward of the cerebrum[1]. The STS is located under the lateral fissure, which is the fissure that separates the temporal lobe, parietal lobe, and frontal lobe[1]. The superior temporal sulcus has an asymmetric structure between the left and right hemisphere, with the STS being longer in the left hemisphere, but deeper in the right hemisphere.[2] This asymmetrical structural organization between hemispheres has only been found to occur in the STS of the human brain.[2] The STS has been shown to produce strong responses when subjects perceive stimuli in research areas that include theory of mind, biological motion, faces, voices, and language.[3][4]

Multisensory processing

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  • Studies reveal multisensory processing capabilities.[5] Research has documented activation in the STS as a result of five specific social inputs, and thus the STS is assumed to be implicated in social perception. It showed increased activation related to: voices versus environmental sounds, stories versus nonsense speech, moving faces versus moving objects, biological motion,[6] and theory of mind (false belief stories versus false physical stories).[7] It is involved in the perception of where others are gazing (joint attention) and is thus important in determining where others' emotions are being directed.[8]

Phonological processing

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  • The majority of studies find it is the middle to the posterior portion of the STS that is involved in phonological processing, with bilateral activation indicated though including a mild left hemisphere bias due to greater observed activation. However, the role of the anterior STS in the ventral pathway of speech comprehension and production has not been ruled out.[9] Evidence for the involvement of the middle portion of the STS in phonological processing comes from repetition-suppression studies, which use fMRI to pinpoint areas of the brain responsible for specialized stimulus involvement by habituating the brain to the stimulus and recording differences in stimulation response. The resulting pattern showed expected results in the middle portion of the STS.[10]

Sign language processing

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Research shows that the Broca's area of the brain is activated during sign language production and processing.[11] Although Broca's area is found in the frontal lobe, it receives connection from the superior temporal gyrus, including the STS.[11] Native signers are people who learned and have been using sign language, such as American Sign Language (ASL), from birth, and/or use it as their first language.[12] They often learn sign language from their parents and continue its use throughout their lifetime[12]. Sign language activates language regions of the brain, including the STS[13]. There have been studies that show activation of the STS while deaf and hearing native signers perceive sign language, suggesting the STS is tied to the linguistic processing aspect of sign language.[14][15] Studies also show that there is greater activation of the middle STS in both deaf and hearing signers who acquired ASL earlier than those who acquired it later.[16]

fMRI

References

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  1. ^ a b Bui, Toai; M Das, Joe (2020), "Neuroanatomy, Cerebral Hemisphere", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31747196, retrieved 2020-11-11
  2. ^ a b Leroy, F; et al. (27 January 2015). "New human-specific brain landmark: the depth asymmetry of superior temporal sulcus". Proceedings of the National Academy of Sciences of the United States of America. 112 (4): 1208–13. Bibcode:2015PNAS..112.1208L. doi:10.1073/pnas.1412389112. PMC 4313811. PMID 25583500.
  3. ^ Beauchamp, MS (September 2015). "The social mysteries of the superior temporal sulcus". Trends in Cognitive Sciences. 19 (9): 489–90. doi:10.1016/j.tics.2015.07.002. PMC 4556565. PMID 26208834.
  4. ^ Deen, B; Koldewyn, K; Kanwisher, N; Saxe, R (November 2015). "Functional Organization of Social Perception and Cognition in the Superior Temporal Sulcus". Cerebral Cortex. 25 (11): 4596–609. doi:10.1093/cercor/bhv111. PMC 4816802. PMID 26048954.
  5. ^ Sours, C; et al. (August 2017). "Cortical multisensory connectivity is present near birth in humans". Brain Imaging and Behavior. 11 (4): 1207–1213. doi:10.1007/s11682-016-9586-6. PMC 5332431. PMID 27581715.
  6. ^ Grossman, E. D.; Blake, R. (2001). "Brain activity evoked by inverted and imagined biological motion". Vision Research. 41 (10–11): 1475–1482. doi:10.1016/s0042-6989(00)00317-5. PMID 11322987.
  7. ^ Beauchamp, MS (September 2015). "The social mysteries of the superior temporal sulcus". Trends in Cognitive Sciences. 19 (9): 489–90. doi:10.1016/j.tics.2015.07.002. PMC 4556565. PMID 26208834.
  8. ^ Campbell, R.; Heywood, C.A.; Cowey, A.; Regard, M.; Landis, T. (1990). "Sensitivity to eye gaze in prosopagnosic patients and monkeys with superior temporal sulcus ablation". Neuropsychologia. 28 (11): 1123–1142. doi:10.1016/0028-3932(90)90050-x. PMID 2290489.
  9. ^ Hickok, Gregory; Poeppel, David (2007-05-01). "The cortical organization of speech processing". Nature Reviews Neuroscience. 8 (5): 393–402. doi:10.1038/nrn2113. ISSN 1471-003X. PMID 17431404.
  10. ^ Vaden Jr., Kenneth I.; Muftuler, L. Tugan; Hickok, Gregory (2010-01-01). "Phonological repetition-suppression in bilateral superior temporal sulci". NeuroImage. 49 (1): 1018–1023. doi:10.1016/j.neuroimage.2009.07.063. PMC 2764799. PMID 19651222.
  11. ^ a b Campbell, R.; MacSweeney, M.; Waters, D. (2007-06-14). "Sign Language and the Brain: A Review". Journal of Deaf Studies and Deaf Education. 13 (1): 3–20. doi:10.1093/deafed/enm035. ISSN 1081-4159.
  12. ^ a b Hauser, Peter; Paludneviciene, Raylene; Supalla, Ted; Bavelier, Daphne (2006-01-01). "American sign language - Sentence reproduction test: Development & implications". Presentations and other scholarship.
  13. ^ Emmorey, Karen; McCullough, Stephen (2009-05). "The bimodal bilingual brain: Effects of sign language experience". Brain and Language. 109 (2–3): 124–132. doi:10.1016/j.bandl.2008.03.005. PMC 2680472. PMID 18471869. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)
  14. ^ Moreno, Antonio; Limousin, Fanny; Dehaene, Stanislas; Pallier, Christophe (2018-02-15). "Brain correlates of constituent structure in sign language comprehension". NeuroImage. 167: 151–161. doi:10.1016/j.neuroimage.2017.11.040. ISSN 1053-8119. PMC 6044420. PMID 29175202.{{cite journal}}: CS1 maint: PMC format (link)
  15. ^ Neville, Helen J.; Bavelier, Daphne; Corina, David; Rauschecker, Josef; Karni, Avi; Lalwani, Anil; Braun, Allen; Clark, Vince; Jezzard, Peter; Turner, Robert (1998-02-03). "Cerebral organization for language in deaf and hearing subjects: Biological constraints and effects of experience". Proceedings of the National Academy of Sciences. 95 (3): 922–929. doi:10.1073/pnas.95.3.922. ISSN 0027-8424. PMID 9448260.
  16. ^ Sadato, Norihiro; Yamada, Hiroki; Okada, Tomohisa; Yoshida, Masaki; Hasegawa, Takehiro; Matsuki, Ken-Ichi; Yonekura, Yoshiharu; Itoh, Harumi (2004-12-08). "Age-dependent plasticity in the superior temporal sulcus in deaf humans: a functional MRI study". BMC Neuroscience. 5 (1): 56. doi:10.1186/1471-2202-5-56. ISSN 1471-2202. PMC 539237. PMID 15588277.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)