Template:2021 National Premier League table
| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification or relegation |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Waterhouse | 10 | 5 | 1 | 4 | 18 | 8 | +10 | 19 | Advance to Playoffs (Semifinals) |
| 2 | Cavalier | 10 | 5 | 2 | 3 | 16 | 9 | +7 | 18 | |
| 3 | Mount Pleasant | 10 | 5 | 2 | 3 | 13 | 10 | +3 | 18 | Advance to Playoffs (Playoff) |
| 4 | Tivoli Gardens | 10 | 4 | 1 | 5 | 14 | 11 | +3 | 17 | |
| 5 | Vere United | 10 | 4 | 3 | 3 | 9 | 7 | +2 | 15 | |
| 6 | Harbour View | 10 | 4 | 3 | 3 | 12 | 11 | +1 | 15 | |
| 7 | Dunbeholden | 10 | 4 | 4 | 2 | 12 | 16 | −4 | 14 | Advance to Bottom Tier |
| 8 | Portmore United | 10 | 4 | 5 | 1 | 11 | 9 | +2 | 13 | |
| 9 | Arnett Gardens | 10 | 2 | 6 | 2 | 8 | 15 | −7 | 8 | |
| 10 | Molynes United | 10 | 1 | 5 | 4 | 8 | 16 | −8 | 7 | |
| 11 | Humble Lions | 10 | 2 | 8 | 0 | 10 | 19 | −9 | 6 |
Updated to match(es) played on 11 September 2021. Source: Jamaica Premier League