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Zangen studies [[neuroplasticity]] in the brain [[reward system]] and the effects of [[Brain stimulation reward|brain stimulation]] on neuroplasticity in [[Mental disorder|psychiatric disorders]] including [[Depression (mood)|depression]], [[addiction]] and [[Attention deficit hyperactivity disorder|attention deficits]].<ref>[https://web.archive.org/web/20180120215231/https://lifeserv.bgu.ac.il/wp/azangen/index.php/personnel-2/curriculum-vitae-and-list-of-publications-zangen/ Abraham Zangen's Lab]</ref>
Zangen studies [[neuroplasticity]] in the brain [[reward system]] and the effects of [[Brain stimulation reward|brain stimulation]] on neuroplasticity in [[Mental disorder|psychiatric disorders]] including [[Depression (mood)|depression]], [[addiction]] and [[Attention deficit hyperactivity disorder|attention deficits]].<ref>[https://web.archive.org/web/20180120215231/https://lifeserv.bgu.ac.il/wp/azangen/index.php/personnel-2/curriculum-vitae-and-list-of-publications-zangen/ Abraham Zangen's Lab]</ref>


During his postdoc at the [[U.S. National Institutes of Health]], Zangen was part of a team that invented a [[magnetic coil]] called the "H coil" for use in [[transcranial magnetic stimulation]] (TMS); the coil allows deeper penetration of the magnetic field into the brain and the procedure whereby the H-coil was applied to TMS became known as deep TMS.<ref name=bersani>{{Cite journal |last=Bersani |first=F.S. |last2=Minichino |first2=A.|last3=Enticott |first3=P.G.|last4=Mazzarini|first4=L. |last5=Khan|first5=N.|last6=Antonacci|first6=G. |last7=Raccah|first7=R.N.|last8=Salviati|first8=M. |last9=Chiai e|first9=R. Delle|title=Deep transcranial magnetic stimulation as a treatment for psychiatric disorders: A comprehensive review |journal=European Psychiatry|volume=28|issue=1|pages=30–39|doi=10.1016/j.eurpsy.2012.02.006|pmid=25038985}}</ref><ref>{{cite journal|last1=George|first1=Mark S.|title=Stimulating the Brain|journal=Scientific American|date=September 2003|volume=289|issue=3|pages=66–73|doi=10.1038/scientificamerican0903-66}}</ref><ref name=Haaretz2005>{{cite news|last1=Rapp|first1=David|title=Field of Dreams|url=https://www.haaretz.com/field-of-dreams-1.150597|work=Haaretz|date=17 February 2005|language=en}}</ref><ref name=blackburn>{{cite web|last=Blackburn|first=Nicky|title=Israel's Brainsway stimulates a magnetic remedy for depression|url=http://israel21c.org/health/israels-brainsway-stimulates-a-magnetic-remedy-for-depression/|publisher=Israel21c|accessdate=11 January 2013|date=19 February 2006}}</ref> The H-coil was patented by the NIH in 2002, and was licensed by the startup company [[Brainsway]] in 2003.<ref name=blackburn/><ref>{{cite web|title=Magnetic Stimulation Shows Promise as the New Wave for Treating Depression |url=http://www.ott.nih.gov/current_issues/archive_Magnetic_Stimulation.aspx|publisher=[[NIH Office of Technology Transfer]]|date=24 July 2007 |deadurl=yes |archiveurl=https://web.archive.org/web/20130330180507/http://www.ott.nih.gov/current_issues/archive_Magnetic_Stimulation.aspx|archivedate=30 March 2013|df=}}</ref> He has continued to do research on applications for deep TMS.<ref>[https://web.archive.org/web/20180120215231/https://lifeserv.bgu.ac.il/wp/azangen/index.php/personnel-2/curriculum-vitae-and-list-of-publications-zangen/ Abraham Zangen's Lab]</ref><ref>{{cite news|last1=Chu|first1=Jennifer|title=A Gentler Way to Jump-Start the Brain|url=https://www.technologyreview.com/s/410150/a-gentler-way-to-jump-start-the-brain/|work=MIT Technology Review|date=May 19, 2008|language=en}}</ref>
During his postdoc at the [[U.S. National Institutes of Health]], Zangen was part of a team that invented a [[magnetic coil]] called the "H coil" for use in [[transcranial magnetic stimulation]] (TMS); the coil allows deeper penetration of the magnetic field into the brain and the procedure whereby the H-coil was applied to TMS became known as deep TMS.<ref name=bersani>{{Cite journal |last=Bersani |first=F.S. |last2=Minichino |first2=A.|last3=Enticott |first3=P.G.|last4=Mazzarini|first4=L. |last5=Khan|first5=N.|last6=Antonacci|first6=G. |last7=Raccah|first7=R.N.|last8=Salviati|first8=M. |last9=Chiai e|first9=R. Delle|title=Deep transcranial magnetic stimulation as a treatment for psychiatric disorders: A comprehensive review |journal=European Psychiatry|volume=28|issue=1|pages=30–39|doi=10.1016/j.eurpsy.2012.02.006|pmid=25038985}}</ref><ref>{{cite journal|last1=George|first1=Mark S.|title=Stimulating the Brain|journal=Scientific American|date=September 2003|volume=289|issue=3|pages=66–73|doi=10.1038/scientificamerican0903-66}}</ref><ref name=Haaretz2005>{{cite news|last1=Rapp|first1=David|title=Field of Dreams|url=https://www.haaretz.com/field-of-dreams-1.150597|work=Haaretz|date=17 February 2005|language=en}}</ref><ref name=blackburn>{{cite web|last=Blackburn|first=Nicky|title=Israel's Brainsway stimulates a magnetic remedy for depression|url=http://israel21c.org/health/israels-brainsway-stimulates-a-magnetic-remedy-for-depression/|publisher=Israel21c|accessdate=11 January 2013|date=19 February 2006}}</ref> The H-coil was patented by the NIH in 2002, and was licensed by the startup company [[Brainsway]] in 2003.<ref name=blackburn/><ref>{{cite web|title=Magnetic Stimulation Shows Promise as the New Wave for Treating Depression |url=http://www.ott.nih.gov/current_issues/archive_Magnetic_Stimulation.aspx|publisher=[[NIH Office of Technology Transfer]]|date=24 July 2007 |deadurl=yes |archiveurl=https://web.archive.org/web/20130330180507/http://www.ott.nih.gov/current_issues/archive_Magnetic_Stimulation.aspx|archivedate=30 March 2013|df=}}</ref> He has continued to do research on applications for deep TMS.<ref>[https://web.archive.org/web/20180120215231/https://lifeserv.bgu.ac.il/wp/azangen/index.php/personnel-2/curriculum-vitae-and-list-of-publications-zangen/ Abraham Zangen's Lab]</ref>


In 2003, Zangen returned to Israel and established a laboratory at the [[Weizmann Institute of Science]], where he attained the rank of Associate Professor in 2010. In 2012 he joined the faculty of [[Ben-Gurion University of the Negev]] as an associate professor and was made a full professor in 2015.<ref name=CV/>
In 2003, Zangen returned to Israel and established a laboratory at the [[Weizmann Institute of Science]], where he attained the rank of Associate Professor in 2010. Since 2012, Zangen has taught at [[Ben Gurion University of the Negev]] and served as Chairman of its Biology-Psychology program.<ref>[http://www.congressmed.com/dddn2014/index.php/2-uncategorised/60-abraham-zangenbd57.html?tmpl=component World Congress on Neurotherapeutics]</ref>He is a Professor of Life Sciences at the Zlotwski Center for Neuroscience.<ref>[http://in.bgu.ac.il/en/zlotowski/Pages/Members.aspx Ben-Gurion University of the Negev, Zlotowski Center for Neuroscience]</ref>

Zangen claims that deep TMS can help smokers quit the habit by boosting networks of neurons in behavior- inhibiting brain regions which will make them better able to resist the urge to smoke.<ref>[https://www.timesofisrael.com/zapping-brain-may-cure-heavy-smokers-study-finds/ Zapping brain may cure heavy smokers, study finds, [[Times of Israel]]]</ref> Zangen and his team are evaluating the potential for disrupting areas of the brain that are abnormally overactive, as in the case of addiction or [[OCD]].<ref>[https://www.technologyreview.com/s/410150/a-gentler-way-to-jump-start-the-brain/ A gentler way to jumpstart the brain, MIT Technology Review]</ref>


==Awards and recognition==
==Awards and recognition==

Revision as of 10:03, 21 March 2018

Abraham Zangen
Born1969
Israel
Scientific career
InstitutionsWeizmann Institute of Science; Ben Gurion University of the Negev

Abraham Zangen (Template:Lang-he-n, born ca 1969, Israel)[1] is a professor of neuroscience, head of the brain stimulation and behavior lab and chair of the psychobiology brain program at the Ben-Gurion University of the Negev (BGU).[2]

Biography

Abraham Zangen earned his B.Sc in pharmacology from the Hebrew University and his Ph.D from the Bar Ilan University in Israel in 1999.[2] He then did a postdoc at the NIH, which ended in 2003.[1]

Scientific career

Zangen studies neuroplasticity in the brain reward system and the effects of brain stimulation on neuroplasticity in psychiatric disorders including depression, addiction and attention deficits.[3]

During his postdoc at the U.S. National Institutes of Health, Zangen was part of a team that invented a magnetic coil called the "H coil" for use in transcranial magnetic stimulation (TMS); the coil allows deeper penetration of the magnetic field into the brain and the procedure whereby the H-coil was applied to TMS became known as deep TMS.[4][5][1][6] The H-coil was patented by the NIH in 2002, and was licensed by the startup company Brainsway in 2003.[6][7] He has continued to do research on applications for deep TMS.[8]

In 2003, Zangen returned to Israel and established a laboratory at the Weizmann Institute of Science, where he attained the rank of Associate Professor in 2010. Since 2012, Zangen has taught at Ben Gurion University of the Negev and served as Chairman of its Biology-Psychology program.[9]He is a Professor of Life Sciences at the Zlotwski Center for Neuroscience.[10]

Zangen claims that deep TMS can help smokers quit the habit by boosting networks of neurons in behavior- inhibiting brain regions which will make them better able to resist the urge to smoke.[11] Zangen and his team are evaluating the potential for disrupting areas of the brain that are abnormally overactive, as in the case of addiction or OCD.[12]

Awards and recognition

Zangen has won prizes for his scientific achievements.[13][14][15] 

Selected papers

  • Zangen, Abraham; Ikemoto, Satoshi; Zadina, James E.; Wise, Roy A. (2002-08-15). "Rewarding and Psychomotor Stimulant Effects of Endomorphin-1: Anteroposterior Differences within the Ventral Tegmental Area and Lack of Effect in Nucleus Accumbens". Journal of Neuroscience. 22 (16): 7225–7233. PMID 12177217.
  • Zangen, Abraham; Solinas, Marcello; Ikemoto, Satoshi; Goldberg, Steven R.; Wise, Roy A. (2006-05-03). "Two Brain Sites for Cannabinoid Reward". Journal of Neuroscience. 26 (18): 4901–4907. doi:10.1523/JNEUROSCI.3554-05.2006. PMID 16672664.
  • Zangen, Abraham; Roth, Yiftach; Voller, Bernhard; Hallett, Mark. "Transcranial magnetic stimulation of deep brain regions: evidence for efficacy of the H-Coil". Clinical Neurophysiology. 116 (4): 775–779. doi:10.1016/j.clinph.2004.11.008. PMID 15792886.
  • Dinur-Klein, Limor; Dannon, Pinhas; Hadar, Aviad; Rosenberg, Oded; Roth, Yiftach; Kotler, Moshe; Zangen, Abraham. "Smoking Cessation Induced by Deep Repetitive Transcranial Magnetic Stimulation of the Prefrontal and Insular Cortices: A Prospective, Randomized Controlled Trial". Biological Psychiatry. 76 (9): 742–749. doi:10.1016/j.biopsych.2014.05.020. PMID 25038985.
  • Carmi, Lior; Alyagon, Uri; Barnea-Ygael, Noam; Zohar, Joseph; Dar, Reuven; Zangen, Abraham. "Clinical and electrophysiological outcomes of deep TMS over the medial prefrontal and anterior cingulate cortices in OCD patients". Brain Stimulation. 11 (1): 158–165. doi:10.1016/j.brs.2017.09.004. PMID 28927961.Open access icon
  • Levkovitz, Yechiel; Isserles, Moshe; Padberg, Frank; Lisanby, Sarah H.; Bystritsky, Alexander; Xia, Guohua; Tendler, Aron; Daskalakis, Zafiris J.; Winston, Jaron L. (2015-02-01). "Efficacy and safety of deep transcranial magnetic stimulation for major depression: a prospective multicenter randomized controlled trial". World Psychiatry. 14 (1): 64–73. doi:10.1002/wps.20199. PMC 4329899. PMID 25655160.

See also

References

  1. ^ a b c Rapp, David (17 February 2005). "Field of Dreams". Haaretz.
  2. ^ a b "CV and Publications". Zangen lab at Ben-Gurion University of the Negev. Archived from the original on 20 January 2018. Retrieved 20 January 2018.
  3. ^ Abraham Zangen's Lab
  4. ^ Bersani, F.S.; Minichino, A.; Enticott, P.G.; Mazzarini, L.; Khan, N.; Antonacci, G.; Raccah, R.N.; Salviati, M.; Chiai e, R. Delle. "Deep transcranial magnetic stimulation as a treatment for psychiatric disorders: A comprehensive review". European Psychiatry. 28 (1): 30–39. doi:10.1016/j.eurpsy.2012.02.006. PMID 25038985.
  5. ^ George, Mark S. (September 2003). "Stimulating the Brain". Scientific American. 289 (3): 66–73. doi:10.1038/scientificamerican0903-66.
  6. ^ a b Blackburn, Nicky (19 February 2006). "Israel's Brainsway stimulates a magnetic remedy for depression". Israel21c. Retrieved 11 January 2013.
  7. ^ "Magnetic Stimulation Shows Promise as the New Wave for Treating Depression". NIH Office of Technology Transfer. 24 July 2007. Archived from the original on 30 March 2013. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  8. ^ Abraham Zangen's Lab
  9. ^ World Congress on Neurotherapeutics
  10. ^ Ben-Gurion University of the Negev, Zlotowski Center for Neuroscience
  11. ^ Zapping brain may cure heavy smokers, study finds, Times of Israel
  12. ^ A gentler way to jumpstart the brain, MIT Technology Review
  13. ^ "Dr. Abraham Zangen - News, Features and Discoveries from the Weizmann Institute of Science". Weizmann Wonder Wander. 2007-09-02. Retrieved 2018-01-04.
  14. ^ "Ben-Gurion University of the Negev - Prof. Abraham Zangen wins Juludan Research Prize". in.bgu.ac.il. Retrieved 2018-01-04. {{cite web}}: Cite has empty unknown parameter: |dead-url= (help)
  15. ^ "Sieratzki Prize for Advances in Neuroscience - Tel Aviv University". www.brain.tau.ac.il. Retrieved 2018-01-04.

External links

Retrieved from "https://en.wikipedia.org/w/index.php?title=Abraham_Zangen&oldid=831591809"