Difference between Indica and Sativa: Difference between revisions

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===Non-psychoactive phytocannabinoids===
===Non-psychoactive phytocannabinoids===
* CBG: 1.3:1<ref>http://www.amjbot.org/content/91/6/966/T4.medium.gif</ref>, cannabigerol has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist
* CBG: 1.3:1<ref>http://www.amjbot.org/content/91/6/966/T4.medium.gif</ref>, cannabigerol has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist
* CBDV+THCV<ref>http://www.amjbot.org/content/91/6/966/T4.medium.gif</ref>, the psychoactive effects of THCV in Cannabis preparations are not well characterized.
* CBDV+THCV<ref>http://www.amjbot.org/content/91/6/966/T4.medium.gif</ref>. THCV has been shown to be a [[CB1 receptor|CB<sub>1</sub> receptor]] [[receptor antagonist|antagonist]], ''i.e.'' it blocks the effects of [[THC]].<ref> Pertwee RG, Thomas A, Stevenson LA, ''et al.'' 2007. The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo. Br. J. Pharmacol. 150(5): 586–94.</ref>



===Other non-psychoactive biochemicals===
===Other non-psychoactive biochemicals===

Revision as of 23:33, 16 February 2012

Indica plants are generally present in Central Asia, whereas the Sativa has been found to grow mostly near the equator. The Indica is not only abundant throughout the world but also grows faster than the Sativa.

Sativa has been observed to give users a feeling of mild euphoria just where the user remains in his senses without letting go of the reality. Indica on the other hand, completely takes the user on a higher euphoria where the user cannot make sense of reality or the hallucinations. In more slang terms, the Sativa gets the user “high”, whereas the Indica gets the user “stoned”. Indica is used more for medicinal purposes whereas the sweet smelling smoke of the Sativa is preferred by habitual smokers looking for a good time. [1]

Indica/Sativa chemotaxonomy ratio

Phytocannabinoids

  • THC (Δ9-tetrahydrocannabinol): 5.6:1[2], most psychoactive cannabinoid in Cannabis.
  • CBC 1:1[3], may contribute to the overall analgesic effects
  • CBD 1:4[4], an isomer of THC who blocks it[5]
  • CBN ?:?: A metabolite of THC, cause drowsiness.

Non-psychoactive phytocannabinoids

  • CBG: 1.3:1[6], cannabigerol has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist
  • CBDV+THCV[7]. THCV has been shown to be a CB1 receptor antagonist, i.e. it blocks the effects of THC.[8]


Other non-psychoactive biochemicals

Effects

The medicinal effects of sativa strains are much more cerebral compared to indica.

Most commercially available indica strains have been selected for low levels of CBD (which is not psychoactive), with some users reporting more of a "stoned" feeling and less of a "high" from C. indica when compared to C. sativa.[11] Indica is typically best for nightime use while Sativa is preffered daytime by most users.

Medical and dependency potential

One diagnostic criteria for DSM-IV Cannabis dependence is "Characteristic withdrawal symptoms from the substance, such as insomnia or difficulty falling asleep, cravings, restlessness, loss of appetite, difficulty concentrating, sweating, mood swings, raise in temperature, depression, irritability, and anger."[12] Indica is mor infamous than Sativa of the described symptoms. In fact, the a sativa-dominated Cannabis strain Jack Herer, is effective in relieving anxiety, nervousness, stress and depression. It is also viewed as a motivational medicine, stimulating energy, creativity and concentration. Jack Herer is well known for both its cerebral high and its strong body high.[13]

See also

References

  1. ^ http://www.differencebetween.com/difference-between-indica-and-sativa/
  2. ^ http://www.amjbot.org/content/91/6/966/T4.medium.gif
  3. ^ http://www.amjbot.org/content/91/6/966/T4.medium.gif
  4. ^ http://www.amjbot.org/content/91/6/966/T4.medium.gif
  5. ^ West, D. P, Ph.D. 1998. Hemp and Marijuana: Myths & Realities. North American Industrial Hemp Council. Retrieved on 23 April 2007
  6. ^ http://www.amjbot.org/content/91/6/966/T4.medium.gif
  7. ^ http://www.amjbot.org/content/91/6/966/T4.medium.gif
  8. ^ Pertwee RG, Thomas A, Stevenson LA, et al. 2007. The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo. Br. J. Pharmacol. 150(5): 586–94.
  9. ^ a b c d e f g Novak J, Zitterl-Eglseer K, Deans SG, Franz CM (2001). "Essential oils of different cultivars of Cannabis sativa L. and their antimicrobial activity". Flavour and Fragrance Journal. 16 (4): 259–262. doi:10.1002/ffj.993.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  10. ^ Essential Oils
  11. ^ "Sativa vs Indica." AMSTERDAM - THE CHANNELS. Web. 05 Dec. 2010. <http://www.channels.nl/knowledge/25700.html>.
  12. ^ Laino, Charlene (7 May 2008). "Withdrawal Symptoms From Smoking Pot?". CBS News. Retrieved 2009-09-05.
  13. ^ "White Jack Herer Effects". Leafly.