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SSR2

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SSR2
Identifiers
AliasesSSR2, TLAP, TRAP-BETA, TRAPB, HSD25, signal sequence receptor subunit 2
External IDsOMIM: 600867; MGI: 1913506; HomoloGene: 2369; GeneCards: SSR2; OMA:SSR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003145

NM_025448

RefSeq (protein)

NP_003136

NP_079724
NP_001343245
NP_001343246
NP_001343247
NP_001343248

Location (UCSC)Chr 1: 156.01 – 156.02 MbChr 3: 88.58 – 88.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene.[5][6]

Function

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The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163479Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041355Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chinen K, Sudo K, Takahashi E, Nakamura Y (Jul 1995). "Isolation and mapping of the human beta-signal sequence receptor gene (SSR2)". Cytogenetics and Cell Genetics. 70 (3–4): 215–7. doi:10.1159/000134036. PMID 7789174.
  6. ^ a b "Entrez Gene: SSR2 signal sequence receptor, beta (translocon-associated protein beta)".

Further reading

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