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2017 Uganda Marburg virus outbreak

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Uganda Marburg outbreak 2017
Initial case= 25 September 2017[1]
Declared ended= 2 December 2017[2]
Uganda
Uganda
Uganda (orthographic projection)
Confirmed cases[3]2
Probable cases[4]1
Deaths[5]3

The 2017 Uganda Marburg virus outbreak was confirmed by the World Health Organization (WHO) on 20 October 2017 after there had been an initial fatality due to the virus.[6]

The Ugandan Ministry of Health indicated that an individual had died of the virus on 19 October; the following day, 20 October, WHO released a press statement regarding the matter. The eastern part of the country is the affected area where the cases have occurred.[1][3] On 22 October, it was reported that 55 individuals were under surveillance for the virus.[7] On 25 October, the number of individuals rose to 155 in terms of contact tracing[8]

Virology and epidemiology

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Main article: Viral hemorrhagic fever
Marburg virus

According to the Centers for Disease Control and Prevention (CDC), the Marburg virus was first recognised in 1967.[9] In terms of diagnosis the presentation is similar to malaria or typhoid fever and therefore not easy to identify (diagnose).[10]

The Marburg virus is considered a filovirus, which is the same as the Ebola virus in terms of viral classification.[11] According to Mehedi, et al. macrophages, monocytes, and dendritic cells, are what the virus attacks due to their importance in the human bodies normal mechanism[12]

According to the World Health Organization there is currently no treatment for the disease.[13] As of 11 November 2017, according to the Ministry of Health no new cases have been reported to this point[14] the report originates from Kampala.

On 8 December the World Health Organization declared the end to the outbreak in the country of Uganda due to two 21-day quarantine periods[15]

Other outbreaks

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Main article: Marburg virus disease § Epidemiology


The table lists a subset of the Marburg virus disease outbreaks, which have occurred specifically in Uganda:

Marburg virus disease outbreaks in Uganda
Year Country Virus Human cases Human deaths Case fatality rate Reference
2007  Uganda MARV & RAVV 2 1 50% [16]
2008  Uganda  Netherlands  United States MARV 2 1 50% [17]
2012  Uganda MARV 18 9 50% [18]
2014  Uganda MARV 1 1 100% [19]
2017  Uganda MARV 3 3 100% [2]

See also

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References

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  1. ^ a b Athumani, Halima (19 October 2017). "Uganda Confirms 1 Death From Ebola-like Marburg Virus". VOA. Archived from the original on 21 October 2017. Retrieved 21 October 2017.
  2. ^ a b "Uganda controls deadly Marburg fever outbreak, WHO says". ABC News. Archived from the original on 8 December 2017. Retrieved 8 December 2017.
  3. ^ a b "Ebola-like Marburg virus kills two in Uganda". Daily Nation. Archived from the original on 21 October 2017. Retrieved 21 October 2017.
  4. ^ "Marburg virus disease – Uganda and Kenya". World Health Organization. Archived from the original on 17 November 2017. Retrieved 16 November 2017.
  5. ^ "Uganda – Marburg Virus Disease (DG ECHO, Ministry of Health)( ECHO Daily Flash of 06 November 2017)". ReliefWeb. 6 November 2017. Archived from the original on 6 November 2017. Retrieved 6 November 2017.
  6. ^ "WHO supports containment of rare virus on Uganda-Kenya border". World Health Organization. Archived from the original on 23 October 2017. Retrieved 21 October 2017.
  7. ^ "Marburg: 55 people under surveillance". The Observer – Uganda. 22 October 2017. Archived from the original on 23 October 2017. Retrieved 23 October 2017.
  8. ^ "Marburg virus disease – Uganda". World Health Organization. Archived from the original on 26 October 2017. Retrieved 16 November 2017.
  9. ^ "Ebola & Marburg | NIH: National Institute of Allergy and Infectious Diseases". www.niaid.nih.gov. Archived from the original on 28 April 2024. Retrieved 21 October 2017.
  10. ^ "Marburg Hemorrhagic Fever (Marburg HF) | CDC". www.cdc.gov. Archived from the original on 19 October 2022. Retrieved 21 October 2017.
  11. ^ Bente, Dennis; Gren, Jason; Strong, James E.; Feldmann, Heinz (2009). "Disease modeling for Ebola and Marburg viruses". Disease Models & Mechanisms. 2 (1–2): 12–17. doi:10.1242/dmm.000471. ISSN 1754-8403. PMC 2615158. PMID 19132113.
  12. ^ Mehedi, Masfique; Groseth, Allison; Feldmann, Heinz; Ebihara, Hideki (2011). "Clinical aspects of Marburg hemorrhagic fever". Future Virology. 6 (9): 1091–1106. doi:10.2217/fvl.11.79. ISSN 1746-0794. PMC 3201746. PMID 22046196.
  13. ^ "Marburg virus disease". World Health Organization. Archived from the original on 28 October 2017. Retrieved 29 October 2017.
  14. ^ "Press Release | Ministry of Health". health.go.ug. Archived from the original on 15 November 2017. Retrieved 16 November 2017.
  15. ^ "Uganda ends Marburg virus disease outbreak". ReliefWeb. 8 December 2017. Archived from the original on 8 December 2017. Retrieved 8 December 2017.
  16. ^ "WHO | Marburg haemorrhagic fever in Uganda". www.who.int. Archived from the original on 8 October 2014. Retrieved 23 October 2017.
  17. ^ "Imported Case of Marburg Hemorrhagic Fever --- Colorado, 2008". cdc.gov. Archived from the original on 23 May 2017. Retrieved 23 October 2017.
  18. ^ "WHO | Marburg haemorrhagic fever in Uganda – update". www.who.int. Archived from the original on 10 August 2014. Retrieved 29 October 2017.
  19. ^ "WHO | Marburg virus disease – Uganda". www.who.int. Archived from the original on 17 November 2014. Retrieved 29 October 2017.

Further reading

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Scholia has a topic profile for 2017 Uganda Marburg virus outbreak.
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