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1,6-alpha-L-fucosidase

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1,6-α-L-Fucosidase
Identifiers
EC no.3.2.1.127
CAS no.102925-35-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
PRIAMprofile
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The enzyme 1,6-α-L-fucosidase (EC 3.2.1.127) catalyses the following chemical reaction

Hydrolysis of 1,6-linkages between α-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin

It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. It is also called α-L-fucosidase.

References

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  • Yazawa S, Madiyalakan R, Chawda RP, Matta KL (1986). "α-L-fucosidase from Aspergillus niger: demonstration of a novel α-L-(1→6)-fucosidase acting on glycopeptides". Biochem. Biophys. Res. Commun. 136 (2): 563–9. doi:10.1016/0006-291X(86)90477-8. PMID 2423086.